GS-441524 is a nucleoside analogue antiviral compound that has been widely referenced in veterinary medicine for the management of feline infectious peritonitis (FIP). As research and treatment experiences have increased over recent years, GS-441524 has become an important compound used in antiviral protocols designed to control viral replication in infected cats.
Feline infectious peritonitis is caused by a mutation of feline coronavirus. Although many cats carry feline coronavirus without severe symptoms, a mutation within the virus can trigger a systemic infection. Once the mutated virus spreads through the body, it may affect organs such as the liver, kidneys, brain, and eyes, leading to serious inflammatory responses.
GS-441524 acts by interfering with the viral RNA replication process. After administration, the compound is converted into an active form that blocks the virus from reproducing inside infected cells. By reducing viral replication, the treatment may help stabilize the condition and allow the cat's immune system to regain control.
This product contains 30mg/ml GS-441524 in a 7ml sterile vial, offering a higher concentration formulation designed to reduce injection volume while maintaining effective dosing levels. The solution is prepared under laboratory production conditions and packaged in sealed vials to maintain product stability during storage and transportation.
The 7ml format provides a practical option for caregivers and veterinary professionals who require a flexible vial size for treatment planning.
| Parameter | Details |
|---|---|
| Product Name | GS-441524 Injection |
| CAS Number | 1191237-69-0 |
| Concentration | 30mg/ml |
| Dosage Form | Injectable Solution |
| Vial Volume | 7ml / vial |
| Function | Treatment for Cat FIP |
| Shelf Life | 1 year from date of manufacture |
| Storage Condition | Room temperature |
| Country of Manufacture | China |
Each vial is labeled with production batch information and expiration date to support product traceability and quality management.
FIP is widely regarded as one of the most serious infectious diseases affecting domestic cats. The disease originates from feline coronavirus (FCoV), which is commonly present in cat populations. In most cases, the virus causes only mild intestinal symptoms, but in certain situations it mutates and becomes capable of spreading throughout the body.
Wet FIP is characterized by the accumulation of fluid in the abdomen or chest cavity. Cats may develop abdominal swelling, breathing difficulty, or lethargy as fluid builds up in body cavities.
Dry FIP does not usually involve visible fluid accumulation. Instead, inflammatory lesions may develop in internal organs such as the liver, kidneys, or lymph nodes.
In some cats, FIP may affect the eyes. Symptoms may include iris discoloration, inflammation, or visual impairment.
When the virus spreads to the central nervous system, neurological symptoms such as poor coordination, tremors, or behavioral changes may appear.
Different forms of FIP may require adjusted treatment plans and antiviral dosage levels.
The dosage of GS-441524 is generally calculated based on the cat's body weight and the specific clinical type of FIP. The following values are commonly referenced as dosage guidelines.
| FIP Type | Suggested Dosage |
|---|---|
| Wet FIP | 0.3 ml × body weight (kg) + 0.1 ml residue |
| Dry FIP | 0.4 ml × body weight (kg) + 0.1 ml residue |
| Eye / Neurological FIP | 0.5 ml × body weight (kg) + 0.1 ml residue |
| Recurrence Cases | 0.6 ml × body weight (kg) + 0.1 ml residue |
Veterinary consultation is recommended to determine the appropriate treatment duration and to monitor the cat's condition during therapy.
To maintain product stability and quality, the following storage guidelines are recommended:
Under proper storage conditions, the product maintains stability for up to one year from the manufacturing date.
This product is supplied as 30mg/ml GS-441524 injection in a 7ml sterile vial. Protective packaging is used during shipment to reduce the risk of damage during transportation.
Typical supply channels include:
This product is intended for veterinary use. Treatment protocols and dosage adjustments should be determined based on the cat's health condition and veterinary recommendations.