Pharmaceutical Intermediates Powder Anti Hair Loss Minoxidil CAS 38304-91-5 In Stock

Minoxidil was the first FDA-approved drug for treating androgenetic alopecia (hair loss). Originally developed as an oral vasodilator for high blood pressure, its side effects included unexpected hair growth and reversal of male baldness. In the 1980s, UpJohn Corporation introduced a 2% topical solution (Rogaine) specifically for treating androgenetic alopecia. Since the 1990s, numerous generic versions have become available for hair loss treatment.

As a vasodilator medication, Minoxidil effectively slows or stops hair loss while promoting regrowth. Available over-the-counter for androgenic alopecia, its benefits typically diminish within months after treatment cessation. Clinical results are most pronounced in younger men (18-41 years), particularly for vertex scalp balding.

Minoxidil is effective for treating refractory and renal hypertension, with stronger antihypertensive effects than hydralazine. Its mechanism involves potassium channel opening in vascular smooth muscle. As a vasodilator antihypertensive, it doesn't cause orthostatic hypotension and maintains long-term efficacy without medication tolerance.

Originally developed for hypertension treatment, Minoxidil gained FDA approval for androgenetic alopecia due to its hair growth side effects observed in clinical use.

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